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ENU-induced phenovariance in mice: inferences from 587 mutations

BACKGROUND: We present a compendium of N-ethyl-N-nitrosourea (ENU)-induced mouse mutations, identified in our laboratory over a period of 10 years either on the basis of phenotype or whole genome and/or whole exome sequencing, and archived in the Mutagenetix database. Our purpose is threefold: 1) to...

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Main Authors: Arnold, Carrie N, Barnes, Michael J, Berger, Michael, Blasius, Amanda L, Brandl, Katharina, Croker, Ben, Crozat, Karine, Du, Xin, Eidenschenk, Celine, Georgel, Philippe, Hoebe, Kasper, Huang, Hua, Jiang, Zhengfan, Krebs, Philippe, La Vine, Diantha, Li, Xiaohong, Lyon, Stephen, Moresco, Eva Marie Y, Murray, Anne R, Popkin, Daniel L, Rutschmann, Sophie, Siggs, Owen M, Smart, Nora G, Sun, Lei, Tabeta, Koichi, Webster, Victoria, Tomisato, Wataru, Won, Sungyong, Xia, Yu, Xiao, Nengming, Beutler, Bruce
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532239/
https://ncbi.nlm.nih.gov/pubmed/23095377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-5-577
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