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TLR4/CD14-mediated PI3K activation is an essential component of interferon-dependent VSV resistance in macrophages
Phosphatidylinositol-3-phosphate kinase (PI3K) has been reported to exhibit anti-inflammatory roles as a negative modulator of the NF-κB pathway (MyD88- and Mal-dependent) triggered upon Toll-like receptor (TLR)4 activation by lipopolysaccharide (LPS). Here, we investigated the role of PI3K on the T...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2834305/ https://ncbi.nlm.nih.gov/pubmed/18339426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2008.02.001 |
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