Flt3 permits survival during infection by rendering dendritic cells competent to activate NK cells

A previously unappreciated signal necessary for dendritic cell (DC)-mediated activation of natural killer (NK) cells during viral infection was revealed by a recessive N-ethyl-N-nitrosourea-induced mutation called warmflash (wmfl). Wmfl homozygotes displayed increased susceptibility to mouse cytomeg...

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Detalhes bibliográficos
Main Authors: Eidenschenk, Céline, Crozat, Karine, Krebs, Philippe, Arens, Ramon, Popkin, Daniel, Arnold, Carrie N., Blasius, Amanda L., Benedict, Chris A., Moresco, Eva Marie Y., Xia, Yu, Beutler, Bruce
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906899/
https://ncbi.nlm.nih.gov/pubmed/20457904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1005186107
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