Medulloblastoma rendered susceptible to NK-cell attack by TGFβ neutralization

BACKGROUND: Medulloblastoma (MB), the most common pediatric brain cancer, presents with a poor prognosis in a subset of patients with high risk disease, or at recurrence, where current therapies are ineffective. Cord blood (CB) natural killer (NK) cells may be promising off-the-shelf effector cells...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Transl Med
Egile Nagusiak: Powell, Allison B., Yadavilli, Sridevi, Saunders, Devin, Van Pelt, Stacey, Chorvinsky, Elizabeth, Burga, Rachel A., Albihani, Shuroug, Hanley, Patrick J., Xu, Zhenhua, Pei, Yanxin, Yvon, Eric S., Hwang, Eugene I., Bollard, Catherine M., Nazarian, Javad, Cruz, Conrad Russell Y.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2019
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6757414/
https://ncbi.nlm.nih.gov/pubmed/31547819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-2055-4
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