Medulloblastoma rendered susceptible to NK-cell attack by TGFβ neutralization

BACKGROUND: Medulloblastoma (MB), the most common pediatric brain cancer, presents with a poor prognosis in a subset of patients with high risk disease, or at recurrence, where current therapies are ineffective. Cord blood (CB) natural killer (NK) cells may be promising off-the-shelf effector cells...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Powell, Allison B., Yadavilli, Sridevi, Saunders, Devin, Van Pelt, Stacey, Chorvinsky, Elizabeth, Burga, Rachel A., Albihani, Shuroug, Hanley, Patrick J., Xu, Zhenhua, Pei, Yanxin, Yvon, Eric S., Hwang, Eugene I., Bollard, Catherine M., Nazarian, Javad, Cruz, Conrad Russell Y.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6757414/
https://ncbi.nlm.nih.gov/pubmed/31547819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-2055-4
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