DIPG-12. OPTIMIZATION OF OSMOTIC PUMP IMPLANTATION FOR DELIVERY OF THERAPEUTICS VIA CONVECTION ENHANCED DELIVERY IN PRECLINICAL MODELS OF DIFFUSE INTRINSIC PONTINE GLIOMA

Diffuse intrinsic pontine gliomas (DIPG) are fatal, high-grade gliomas arising in pons of children. Due to the blood brain barrier (BBB), it is difficult to effectively deliver chemotherapy agents into the tumor. Convection-enhanced delivery (CED) has been shown to deliver agents into tissues via a...

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Vydáno v:Neuro Oncol
Hlavní autoři: Knudson, Kathleen, Yadavilli, Sridevi, Packer, Roger, Nazarian, Javad
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474980/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.027
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