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DIPG-12. OPTIMIZATION OF OSMOTIC PUMP IMPLANTATION FOR DELIVERY OF THERAPEUTICS VIA CONVECTION ENHANCED DELIVERY IN PRECLINICAL MODELS OF DIFFUSE INTRINSIC PONTINE GLIOMA
Diffuse intrinsic pontine gliomas (DIPG) are fatal, high-grade gliomas arising in pons of children. Due to the blood brain barrier (BBB), it is difficult to effectively deliver chemotherapy agents into the tumor. Convection-enhanced delivery (CED) has been shown to deliver agents into tissues via a...
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| Pubblicato in: | Neuro Oncol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5474980/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.027 |
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