ET-64 PRE-CLINICAL ASSESSMENT OF DISSOCIATIVE STEROIDS AS DEXAMETHASONE SUBSTITUTE FOR TREATMENT IN DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)

BACKGROUND: Although corticosteroids are widely used to treat cancer, cerebral edema, and other inflammatory disorders, their exact mechanism of action is poorly understood and less toxic alternatives are needed. The purpose of this study was to use a genetically engineered DIPG murine model to cond...

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Auteurs principaux: Wells, Elizabeth, Khambampati, Madhuri, Yadavilli, Sridevi, Damsker, Jesse, Hoffman, Eric, Packer, Roger, Nazarian, Javad
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2014
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218161/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou255.61
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