DIPG-50. CHROMATIN IMMUNOPRECIPITATION OF DIFFUSE INTRINSIC PONTINE GLIOMA TUMOR TISSUE IS FEASIBLE AND SHOW DIFFERENT ENRICHMENT COMPARED TO PRIMARY CELL LINE

Diffuse intrinsic pontine glioma (DIPG) is the leading cause of mortality in pediatric central nervous system cancers. Histone mutations are found in >80% of DIPG cases. The most common mutation is histone 3.3 at position 27 resulting in lysine to methionine(H3.3K27M). This mutation results in ep...

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Publicado no:Neuro Oncol
Main Authors: Kim, Yong Yean, Andricovich, Jaclyn, Yadavilli, Sridevi, Kambhampati, Madhuri, Tzatsos, Alexandros, Nazarian, Javad
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012668/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.143
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