DIPG-50. CHROMATIN IMMUNOPRECIPITATION OF DIFFUSE INTRINSIC PONTINE GLIOMA TUMOR TISSUE IS FEASIBLE AND SHOW DIFFERENT ENRICHMENT COMPARED TO PRIMARY CELL LINE

Diffuse intrinsic pontine glioma (DIPG) is the leading cause of mortality in pediatric central nervous system cancers. Histone mutations are found in >80% of DIPG cases. The most common mutation is histone 3.3 at position 27 resulting in lysine to methionine(H3.3K27M). This mutation results in ep...

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Vydáno v:Neuro Oncol
Hlavní autoři: Kim, Yong Yean, Andricovich, Jaclyn, Yadavilli, Sridevi, Kambhampati, Madhuri, Tzatsos, Alexandros, Nazarian, Javad
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012668/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.143
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