In Vivo Role of Flt3 Ligand and Dendritic Cells in NK Cell Homeostasis

IL-15 is required for NK cell development and homeostasis in vivo. Because IL-15 is presented in trans via its high-affinity IL-15Rα–chain to cells expressing the IL-15Rβγ complex, we postulated that certain IL-15–bearing cells must be required for NK cell homeostasis. Using IL-15(WT/WT) and IL-15(−...

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Bibliografiske detaljer
Main Authors: Guimond, Martin, Freud, Aharon G., Mao, Hsiaoyin C., Yu, Jianhua, Blaser, Bradley W., Leong, Jeffrey W., Vandeusen, Jeffrey B., Dorrance, Adrienne, Zhang, Jianying, Mackall, Crystal L., Caligiuri, Michael A.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924750/
https://ncbi.nlm.nih.gov/pubmed/20142363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900685
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