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Conservation of Flexible Residue Clusters among Structural and Functional Enzyme Homologues

Conformational flexibility between structural ensembles is an essential component of enzyme function. Although the broad dynamical landscape of proteins is known to promote a number of functional events on multiple time scales, it is yet unknown whether structural and functional enzyme homologues re...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gagné, Donald, Charest, Laurie-Anne, Morin, Sébastien, Kovrigin, Evgenii L., Doucet, Nicolas
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531744/
https://ncbi.nlm.nih.gov/pubmed/23135272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.394866
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