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Role of the Wrist Domain in the Response of the Epithelial Sodium Channel to External Stimuli

The epithelial Na(+) channel (ENaC) is regulated by a variety of external factors that alter channel activity by inducing conformational changes within its large extracellular region that are transmitted to the gate. The wrist domain consists of small linkers connecting the extracellular region to t...

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Autori principali: Shi, Shujie, Carattino, Marcelo D., Kleyman, Thomas R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531719/
https://ncbi.nlm.nih.gov/pubmed/23144453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.421743
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