WLS inhibits melanoma cell proliferation through the β-catenin signalling pathway and induces spontaneous metastasis

Elevated levels of nuclear β-catenin are associated with higher rates of survival in patients with melanoma, raising questions as to how ß-catenin is regulated in this context. In the present study, we investigated the formal possibility that the secretion of WNT ligands that stabilize ß-catenin may...

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Detalhes bibliográficos
Main Authors: Yang, Pei-Tzu, Anastas, Jamie N, Toroni, Rachel A, Shinohara, Michi M, Goodson, Jamie M, Bosserhoff, Anja K, Chien, Andy J, Moon, Randall T
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2012
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Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531604/
https://ncbi.nlm.nih.gov/pubmed/23129487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201201486
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