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CTLA-4 Is a Direct Target of Wnt/β-Catenin Signaling and Is Expressed in Human Melanoma Tumors

Our goal was to identify genes regulated by Wnt/β-catenin signaling in melanoma cells, as this pathway has been implicated in melanocyte development and in melanoma biology. We therefore undertook transcriptional profiling of UACC 1273 human melanoma cells following treatment with recombinant Wnt-3a...

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Main Authors: Shah, Kavita V., Chien, Andy J., Yee, Cassian, Moon, Randall T.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135173/
https://ncbi.nlm.nih.gov/pubmed/18563180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2008.170
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