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High-Throughput Mutation Profiling of Primary and Metastatic Endometrial Cancers Identifies KRAS, FGFR2 and PIK3CA to Be Frequently Mutated

BACKGROUND: Despite being the most common pelvic gynecologic malignancy in industrialized countries, no targeted therapies are available for patients with metastatic endometrial carcinoma. In order to improve treatment, underlying molecular characteristics of primary and metastatic disease must be e...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Krakstad, Camilla, Birkeland, Even, Seidel, Danila, Kusonmano, Kanthida, Petersen, Kjell, Mjøs, Siv, Hoivik, Erling A., Wik, Elisabeth, Halle, Mari Kyllesø, Øyan, Anne M., Kalland, Karl-Henning, Werner, Henrica Maria Johanna, Trovik, Jone, Salvesen, Helga
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531332/
https://ncbi.nlm.nih.gov/pubmed/23300780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052795
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