High-Throughput Mutation Profiling of Primary and Metastatic Endometrial Cancers Identifies KRAS, FGFR2 and PIK3CA to Be Frequently Mutated

BACKGROUND: Despite being the most common pelvic gynecologic malignancy in industrialized countries, no targeted therapies are available for patients with metastatic endometrial carcinoma. In order to improve treatment, underlying molecular characteristics of primary and metastatic disease must be e...

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Hlavní autoři: Krakstad, Camilla, Birkeland, Even, Seidel, Danila, Kusonmano, Kanthida, Petersen, Kjell, Mjøs, Siv, Hoivik, Erling A., Wik, Elisabeth, Halle, Mari Kyllesø, Øyan, Anne M., Kalland, Karl-Henning, Werner, Henrica Maria Johanna, Trovik, Jone, Salvesen, Helga
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531332/
https://ncbi.nlm.nih.gov/pubmed/23300780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052795
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