Hypomethylation of the CTCFL/BORIS promoter and aberrant expression during endometrial cancer progression suggests a role as an Epi-driver gene

Cancers arise through accumulating genetic and epigenetic alterations, considered relevant for phenotype and approaches to targeting new therapies. We investigated a unique collection of endometrial cancer precursor samples and clinically annotated primary and metastatic lesions for two evolutionary...

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Hauptverfasser: Hoivik, Erling A., Kusonmano, Kanthida, Halle, Mari K., Berg, Anna, Wik, Elisabeth, Werner, Henrica M. J., Petersen, Kjell, Oyan, Anne M., Kalland, Karl-Henning, Krakstad, Camilla, Trovik, Jone, Widschwendter, Martin, Salvesen, Helga B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2014
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Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011582/
https://ncbi.nlm.nih.gov/pubmed/24658009
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