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Recent Advances in the Structural Mechanisms of DNA Glycosylases

DNA glycosylases safeguard the genome by locating and excising a diverse array of aberrant nucleobases created from oxidation, alkylation, and deamination of DNA. Since the discovery 28 years ago that these enzymes employ a base flipping mechanism to trap their substrates, six different protein arch...

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Bibliografski detalji
Glavni autori: Brooks, Sonja C., Adhikary, Suraj, Rubinson, Emily H., Eichman, Brandt F.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530658/
https://ncbi.nlm.nih.gov/pubmed/23076011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2012.10.005
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