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The substrate binding interface of alkylpurine DNA glycosylase AlkD
Tandem helical repeats have emerged as an important DNA binding architecture. DNA glycosylase AlkD, which excises N3- and N7-alkylated nucleobases, uses repeating helical motifs to bind duplex DNA and to selectively pause at non-Watson-Crick base pairs. Remodeling of the DNA backbone promotes nucleo...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4039204/ https://ncbi.nlm.nih.gov/pubmed/24286669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2013.10.009 |
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