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A catalytic role for C-H/π interactions in base excision repair by Bacillus cereus DNA glycosylase AlkD
DNA glycosylases protect genomic integrity by locating and excising aberrant nucleobases. Substrate recognition and excision usually takes place in an extrahelical conformation, which is often stabilized by π-stacking interactions between the lesion nucleobase and aromatic side chains in the glycosy...
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| Publicado no: | J Am Chem Soc |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5034759/ https://ncbi.nlm.nih.gov/pubmed/27571247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b07399 |
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