A carregar...
Depurination of N7-methylguanine by DNA glycosylase AlkD is dependent on the DNA backbone
DNA glycosylase AlkD excises N7-methylguanine (7mG) by a unique but unknown mechanism, in which the damaged nucleotide is positioned away from the protein and the phosphate backbone distorted. Here, we show by methylphosphonate substitution that a phosphate proximal to the lesion has a significant e...
Na minha lista:
| Main Authors: | , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3852881/ https://ncbi.nlm.nih.gov/pubmed/24090276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi401195r |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|