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Recent Advances in the Structural Mechanisms of DNA Glycosylases
DNA glycosylases safeguard the genome by locating and excising a diverse array of aberrant nucleobases created from oxidation, alkylation, and deamination of DNA. Since the discovery 28 years ago that these enzymes employ a base flipping mechanism to trap their substrates, six different protein arch...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3530658/ https://ncbi.nlm.nih.gov/pubmed/23076011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2012.10.005 |
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