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Identification of beta-amyloid-binding sites on transthyretin
Transthyretin (TTR) binds to the Alzheimer-related peptide beta-amyloid (Aβ), and may protect against Aβ-induced neurotoxicity. In this work, the specific domains on TTR involved with binding to Aβ were probed. An array was constructed of peptides derived from overlapping sequences from TTR. Strong...
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| Główni autorzy: | , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Oxford University Press
2012
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3530273/ https://ncbi.nlm.nih.gov/pubmed/22670059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzs026 |
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