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Pharmacokinetics of moxalactam in subjects with various degrees of renal dysfunction.

We have examined the pharmacokinetics of moxalactam (LY127935) in 36 subjects with various degrees of renal dysfunction. Creatinine clearance (Ccr)/1.73 m2 ranged from zero to 135.8 ml/min. After a 1-g administration of moxalactam intravenously, the volume of distribution was 20.6 /+- 9.5 liters (0....

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書目詳細資料
發表在:Antimicrob Agents Chemother
Principais autores: Bolton, W K, Scheld, W M, Spyker, D A, Overby, T L, Sande, M A
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 1980
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在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352992/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6453555/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.18.6.933
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