Pharmacokinetics of moxalactam in subjects with various degrees of renal dysfunction.

We have examined the pharmacokinetics of moxalactam (LY127935) in 36 subjects with various degrees of renal dysfunction. Creatinine clearance (Ccr)/1.73 m2 ranged from zero to 135.8 ml/min. After a 1-g administration of moxalactam intravenously, the volume of distribution was 20.6 /+- 9.5 liters (0....

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Bolton, W K, Scheld, W M, Spyker, D A, Overby, T L, Sande, M A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1980
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352992/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6453555/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.18.6.933
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