Pharmacokinetics of moxalactam in subjects with various degrees of renal dysfunction.

We have examined the pharmacokinetics of moxalactam (LY127935) in 36 subjects with various degrees of renal dysfunction. Creatinine clearance (Ccr)/1.73 m2 ranged from zero to 135.8 ml/min. After a 1-g administration of moxalactam intravenously, the volume of distribution was 20.6 /+- 9.5 liters (0....

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Bolton, W K, Scheld, W M, Spyker, D A, Overby, T L, Sande, M A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1980
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352992/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6453555/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.18.6.933
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