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Pharmacokinetics of moxalactam in subjects with various degrees of renal dysfunction.

We have examined the pharmacokinetics of moxalactam (LY127935) in 36 subjects with various degrees of renal dysfunction. Creatinine clearance (Ccr)/1.73 m2 ranged from zero to 135.8 ml/min. After a 1-g administration of moxalactam intravenously, the volume of distribution was 20.6 /+- 9.5 liters (0....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bolton, W K, Scheld, W M, Spyker, D A, Overby, T L, Sande, M A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1980
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC352992/
https://ncbi.nlm.nih.gov/pubmed/6453555
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