Pharmacokinetics of moxalactam in subjects with various degrees of renal dysfunction.

We have examined the pharmacokinetics of moxalactam (LY127935) in 36 subjects with various degrees of renal dysfunction. Creatinine clearance (Ccr)/1.73 m2 ranged from zero to 135.8 ml/min. After a 1-g administration of moxalactam intravenously, the volume of distribution was 20.6 /+- 9.5 liters (0....

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Bolton, W K, Scheld, W M, Spyker, D A, Overby, T L, Sande, M A
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1980
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352992/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6453555/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.18.6.933
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