Pharmacokinetics of moxalactam in subjects with various degrees of renal dysfunction.

We have examined the pharmacokinetics of moxalactam (LY127935) in 36 subjects with various degrees of renal dysfunction. Creatinine clearance (Ccr)/1.73 m2 ranged from zero to 135.8 ml/min. After a 1-g administration of moxalactam intravenously, the volume of distribution was 20.6 /+- 9.5 liters (0....

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Bolton, W K, Scheld, W M, Spyker, D A, Overby, T L, Sande, M A
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1980
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352992/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6453555/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.18.6.933
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