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Tetramethylenedisulfotetramine Alters Ca(2+) Dynamics in Cultured Hippocampal Neurons: Mitigation by NMDA Receptor Blockade and GABA(A) Receptor-Positive Modulation
Tetramethylenedisulfotetramine (TETS) is a potent convulsant that is considered a chemical threat agent. We characterized TETS as an activator of spontaneous Ca(2+) oscillations and electrical burst discharges in mouse hippocampal neuronal cultures at 13–17 days in vitro using FLIPR Fluo-4 fluoresce...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3529644/ https://ncbi.nlm.nih.gov/pubmed/22889812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfs244 |
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