GABA(A) receptor target of tetramethylenedisulfotetramine

Use of the highly toxic and easily prepared rodenticide tetramethylenedisulfotetramine (TETS) was banned after thousands of accidental or intentional human poisonings, but it is of continued concern as a chemical threat agent. TETS is a noncompetitive blocker of the GABA type A receptor (GABA(A)R),...

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Autores principales: Zhao, Chunqing, Hwang, Sung Hee, Buchholz, Bruce A., Carpenter, Timothy S., Lightstone, Felice C., Yang, Jun, Hammock, Bruce D., Casida, John E.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2014
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060666/
https://ncbi.nlm.nih.gov/pubmed/24912155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1407379111
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