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New GABA/Glutamate Receptor Target for [(3)H]Isoxazoline Insecticide

The highly-effective and selective isoxazoline insecticide A1443 is known to potently displace [(3)H]ethynylbicycloorthobenzoate ([(3)H]EBOB) binding to house fly head membranes with an IC(50) of 0.2 nM in a manner characteristic of GABA-gated chloride channel antagonists. To further define its mode...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: García-Reynaga, Pablo, Zhao, Chunqing, Sarpong, Richmond, Casida, John E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731417/
https://ncbi.nlm.nih.gov/pubmed/23465072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx400055p
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