Characterization of Seizures Induced by Acute and Repeated Exposure to Tetramethylenedisulfotetramine

Tetramethylenedisulfotetramine (tetramine; TETS) is a potent convulsant poison that is considered to be a chemical threat agent. To provide a basis for the investigation of antidotes for TETS-induced seizures, we characterized the convulsant activity of TETS in mice and rats when administered by the...

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Detalhes bibliográficos
Main Authors: Zolkowska, Dorota, Banks, Christopher N., Dhir, Ashish, Inceoglu, Bora, Sanborn, James R., McCoy, Mark R., Bruun, Donald A., Hammock, Bruce D., Lein, Pamela J., Rogawski, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2012
Assuntos:
Neuropharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3336809/
https://ncbi.nlm.nih.gov/pubmed/22328574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.190579
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