Identification of Retinol Binding Protein 1 Promoter Hypermethylation in Isocitrate Dehydrogenase 1 and 2 Mutant Gliomas

BACKGROUND: Mutations in isocitrate dehydrogenase 1 (IDH1) and associated CpG island hypermethylation represent early events in the development of low-grade gliomas and secondary glioblastomas. To identify candidate tumor suppressor genes whose promoter methylation may contribute to gliomagenesis, w...

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Autori principali: Chou, Arthur P., Chowdhury, Reshmi, Li, Sichen, Chen, Weidong, Kim, Andrew J., Piccioni, David E., Selfridge, Julia M., Mody, Reema R., Chang, Stephen, Lalezari, Shadi, Lin, Jeffrey, Sanchez, Desiree E., Wilson, Ryan W., Garrett, Matthew C., Harry, Bret, Mottahedeh, Jack, Nghiemphu, Phioanh L., Kornblum, Harley I., Mischel, Paul S., Prins, Robert M., Yong, William H., Cloughesy, Timothy, Nelson, Stanley F., Liau, Linda M., Lai, Albert
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529615/
https://ncbi.nlm.nih.gov/pubmed/22945948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djs357
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