The composition and signaling of the IL-35 receptor are unconventional

Interleukin-35 (IL-35) belongs to the IL-12 family of heterodimeric cytokines but has a distinct functional profile. IL-35 suppresses T cell proliferation and converts naïve T cells into IL-35-producing iTr35. Here we show that IL-35 signals through a unique IL-12Rβ2:gp130 heterodimer or via homodim...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Collison, Lauren W., Delgoffe, Greg M., Guy, Clifford S., Vignali, Kate M., Chaturvedi, Vandana, Fairweather, DeLisa, Satoskar, Abhay R., Garcia, K. Christopher, Hunter, Christopher A., Drake, Charles G., Murray, Peter J., Vignali, Dario A. A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529151/
https://ncbi.nlm.nih.gov/pubmed/22306691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2227
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