The composition and signaling of the IL-35 receptor are unconventional

Interleukin-35 (IL-35) belongs to the IL-12 family of heterodimeric cytokines but has a distinct functional profile. IL-35 suppresses T cell proliferation and converts naïve T cells into IL-35-producing iTr35. Here we show that IL-35 signals through a unique IL-12Rβ2:gp130 heterodimer or via homodim...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Collison, Lauren W., Delgoffe, Greg M., Guy, Clifford S., Vignali, Kate M., Chaturvedi, Vandana, Fairweather, DeLisa, Satoskar, Abhay R., Garcia, K. Christopher, Hunter, Christopher A., Drake, Charles G., Murray, Peter J., Vignali, Dario A. A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529151/
https://ncbi.nlm.nih.gov/pubmed/22306691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2227
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller