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Orai-STIM–mediated Ca(2)(+) release from secretory granules revealed by a targeted Ca(2+) and pH probe
Secretory granules (SGs) sequester significant calcium. Understanding roles for this calcium and potential mechanisms of release is hampered by the difficulty of measuring SG calcium directly in living cells. We adapted the Förster resonance energy transfer-based D1-endoplasmic reticulum (ER) probe...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3529049/ https://ncbi.nlm.nih.gov/pubmed/23184982 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1218247109 |
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