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Optimising Immunogenicity with Viral Vectors: Mixing MVA and HAdV-5 Expressing the Mycobacterial Antigen Ag85A in a Single Injection
The Bacillus Calmette - Guerin (BCG) vaccine provides a critical but limited defense against Mycobacterium tuberculosis (M.tb). More than 60 years after the widespread introduction of BCG, there is an urgent need for a better vaccine. A large body of pre-clinical research continues to support ongoin...
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Main Authors: | , , , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Public Library of Science
2012
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3528774/ https://ncbi.nlm.nih.gov/pubmed/23284637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050447 |
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