Evaluation of the Safety and Immunogenicity of a Candidate Tuberculosis Vaccine, MVA85A, Delivered by Aerosol to the Lungs of Macaques

Tuberculosis (TB) is a reemerging disease. The only available vaccine, Mycobacterium bovis BCG, is delivered intradermally and confers highly variable efficacy against pulmonary disease. There is an urgent need for improved vaccination strategies. Murine studies suggest that immunizations delivered...

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Detalhes bibliográficos
Main Authors: White, A. D., Sibley, L., Dennis, M. J., Gooch, K., Betts, G., Edwards, N., Reyes-Sandoval, A., Carroll, M. W., Williams, A., Marsh, P. D., McShane, H., Sharpe, S. A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3647747/
https://ncbi.nlm.nih.gov/pubmed/23446219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00690-12
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