Improvement of BCG protective efficacy with a novel chimpanzee adenovirus and a modified vaccinia Ankara virus both expressing Ag85A

A replication-deficient chimpanzee adenovirus expressing Ag85A (ChAdOx1.85A) was assessed, both alone and in combination with modified vaccinia Ankara also expressing Ag85A (MVA85A), for its immunogenicity and protective efficacy against a Mycobacterium tuberculosis (M.tb) challenge in mice. Naïve a...

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Publicado no:Vaccine
Main Authors: Stylianou, E., Griffiths, K.L., Poyntz, H.C., Harrington-Kandt, R., Dicks, M.D., Stockdale, L., Betts, G., McShane, H.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4678294/
https://ncbi.nlm.nih.gov/pubmed/26478198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2015.10.017
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