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Aneuploidy-induced delaminating cells drive tumorigenesis in Drosophila epithelia
Genomic instability has been observed in essentially all sporadic carcinomas. Here we use Drosophila epithelial cells to address the role of chromosomal instability in cancer development as they have proved useful for elucidating the molecular mechanisms underlying tumorigenic growth. We first show...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3528526/ https://ncbi.nlm.nih.gov/pubmed/23184991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1206675109 |
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