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Aneuploidy, cell delamination and tumorigenesis in Drosophila epithelia
Chromosomal instability (CIN) is a common feature in human cancer, and highly aneuploid tumors are frequently associated with poor prognosis; however, the molecular and cellular mechanisms underlying CIN-induced tumorigenesis are poorly understood. Here we review recent findings about the role of CI...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Landes Bioscience
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3610720/ https://ncbi.nlm.nih.gov/pubmed/23422863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.23949 |
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