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Feedback amplification loop drives malignant growth in epithelial tissues

Interactions between cells bearing oncogenic mutations and the surrounding microenvironment, and cooperation between clonally distinct cell populations, can contribute to the growth and malignancy of epithelial tumors. The genetic techniques available in Drosophila have contributed to identify impor...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Muzzopappa, Mariana, Murcia, Lada, Milán, Marco
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584413/
https://ncbi.nlm.nih.gov/pubmed/28808034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1701791114
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