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Tumor suppressor roles of CENP-E and Nsl1 in Drosophila epithelial tissues
Depletion of spindle assembly checkpoint (SAC) genes in Drosophila epithelial tissues leads to JNK-dependent programmed cell death and additional blockade of the apoptotic program drives tumorigenesis. A recent report proposes that chromosomal instability (CIN) is not the driving force in the tumori...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4050142/ https://ncbi.nlm.nih.gov/pubmed/24626182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.28417 |
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