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A feedback amplification loop between stem cells and their progeny promotes tissue regeneration and tumorigenesis
Homeostatic renewal of many adult tissues requires balanced self-renewal and differentiation of local stem cells, but the underlying mechanisms are poorly understood. Here we identified a novel feedback mechanism in controlling intestinal regeneration and tumorigenesis in Drosophila. Sox21a, a group...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4905741/ https://ncbi.nlm.nih.gov/pubmed/27187149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.14330 |
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