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PTEN regulates TLR5-induced intestinal inflammation by controlling Mal/TIRAP recruitment
Defective IL-10 allele is a risk factor for intestinal inflammation. Indeed, IL-10(−/−) mice are predisposed to spontaneous colitis in the presence of intestinal microbiota, indicating that microbial factors contribute to developing intestinal inflammation. By recognizing flagellin, TLR5 plays a qui...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Federation of American Societies for Experimental Biology
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3528317/ https://ncbi.nlm.nih.gov/pubmed/23038756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-217596 |
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