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TRIF Modulates TLR5-dependent Responses by Inducing Proteolytic Degradation of TLR5
Proteolytic modification of pattern recognition receptors and their signaling adaptor molecules has recently emerged as an essential cellular event to regulate immune and inflammatory responses. Here we show that the TIR domain containing adaptor-inducing interferon-β (TRIF), an adaptor molecule med...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2898416/ https://ncbi.nlm.nih.gov/pubmed/20452988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.115022 |
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