TRIF Mediates Toll-like Receptor 5-induced Signaling in Intestinal Epithelial Cells

Toll-like receptors (TLRs) associate with adaptor molecules (MyD88, Mal/TIRAP, TRAM, and TRIF) to mediate signaling of host-microbial interaction. For instance, TLR4 utilizes the combination of both Mal/TIRAP-MyD88 (MyD88-dependent pathway) and TRAM-TRIF (MyD88-independent pathway). However, TLR5, t...

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Bibliographic Details
Main Authors: Choi, Yoon Jeong, Im, Eunok, Chung, Hyo Kyun, Pothoulakis, Charalabos, Rhee, Sang Hoon
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988362/
https://ncbi.nlm.nih.gov/pubmed/20855887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.158394
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