The mRNA-stabilizing Factor HuR Protein Is Targeted by β-TrCP Protein for Degradation in Response to Glycolysis Inhibition

The mRNA-stabilizing protein HuR acts a stress response protein whose function and/or protein stability are modulated by diverse stress stimuli through posttranslational modifications. Here, we report a novel mechanism by which metabolic stress facilitates proteasomal degradation of HuR in cancer ce...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chu, Po-Chen, Chuang, Hsiao-Ching, Kulp, Samuel K., Chen, Ching-Shih
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2012
Gaiak:
Metabolism
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527950/
https://ncbi.nlm.nih.gov/pubmed/23115237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.393678
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