PheVI:09 (Phe6.44) as a Sliding Microswitch in Seven-transmembrane (7TM) G Protein-coupled Receptor Activation

In seven-transmembrane (7TM), G protein-coupled receptors, highly conserved residues function as microswitches, which alternate between different conformations and interaction partners in an extended allosteric interface between the transmembrane segments performing the large scale conformational ch...

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Detalles Bibliográficos
Autores principales: Valentin-Hansen, Louise, Holst, Birgitte, Frimurer, Thomas M., Schwartz, Thue W.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527938/
https://ncbi.nlm.nih.gov/pubmed/23135271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.395137
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