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PheVI:09 (Phe6.44) as a Sliding Microswitch in Seven-transmembrane (7TM) G Protein-coupled Receptor Activation

In seven-transmembrane (7TM), G protein-coupled receptors, highly conserved residues function as microswitches, which alternate between different conformations and interaction partners in an extended allosteric interface between the transmembrane segments performing the large scale conformational ch...

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Autors principals: Valentin-Hansen, Louise, Holst, Birgitte, Frimurer, Thomas M., Schwartz, Thue W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527938/
https://ncbi.nlm.nih.gov/pubmed/23135271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.395137
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