Activation of Liver X Receptor Induces Macrophage Interleukin-5 Expression

IL-5 stimulates production of T15/EO6 IgM antibodies that can block the uptake of oxidized low density lipoprotein by macrophages, whereas a deficiency in macrophage IL-5 expression accelerates development of atherosclerosis. Liver X receptors (LXRs) are ligand-activated transcription factors that c...

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Detalhes bibliográficos
Main Authors: Chen, Yuanli, Duan, Yajun, Kang, Yanhua, Yang, Xiaoxiao, Jiang, Meixiu, Zhang, Ling, Li, Guangliang, Yin, Zhinan, Hu, Wenquan, Dong, Pengzhi, Li, Xiaoju, Hajjar, David P., Han, Jihong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Lipids
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527921/
https://ncbi.nlm.nih.gov/pubmed/23150660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.403394
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