Inhibition of ERK1/2 and Activation of Liver X Receptor Synergistically Induce Macrophage ABCA1 Expression and Cholesterol Efflux

ATP-binding cassette transporter A1 (ABCA1), a molecule mediating free cholesterol efflux from peripheral tissues to apoAI and high density lipoprotein (HDL), inhibits the formation of lipid-laden macrophage/foam cells and the development of atherosclerosis. ERK1/2 are important signaling molecules...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Zhou, Xiaoye, Yin, Zhinan, Guo, Xianzhi, Hajjar, David P., Han, Jihong
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Lipids
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825427/
https://ncbi.nlm.nih.gov/pubmed/20037141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.073601
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares